Author Archives: Alan

TWiV 183: Bats out of hell

Connor joins the TWiV team to discuss bats as hosts for major mammalian paramyxoviruses. Links for this episode: NIH response to Osterholm letter (pdf) Who’s afraid of the big, bad bioterrorist? Bats host major mammalian paramyxoviruses (Nature Comm) TWiV on Facebook Letters read on TWiV … Continue reading

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The NEC-4 Security Scam

A few decades ago, scientists at Lawrence Livermore National Laboratory (LLNL) in California developed a computer program called the Numerical Electromagnetic Code, or NEC. This set of algorithms allowed researchers to build computer models of radio antennas so they could … Continue reading

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TWiV 182: One flu over the ferrets’ nest

Hosts: Vincent Racaniello, Rich Condit, Alan Dove, and Michael J. Imperiale Michael joins the TWiV crew to discuss the recently published influenza H5N1 transmission paper and how it was viewed by the NSABB. Links for this episode: About the NSABB The Kawaoka paper (Nature) Mutant flu paper published … Continue reading

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One of the two H5N1 influenza papers that fueled this brouhaha has finally seen the light of day. Rather than rehash what others have already said so well, I refer readers to the excellent summaries by Vincent Racaniello and Ed … Continue reading

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Tools of the Trade: Timestamps and Text Editors

Quoting people accurately is a mundane but crucial task in my daily work. Over the years, I’ve tried a variety of approaches, but I think I’ve finally evolved the most efficient system for handling it. When I’m conducting an interview … Continue reading

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TWiV 181: ORFan poxviruses and nIRFing prions

Hosts: Vincent Racaniello, Rich Condit, and Kathy Spindler Vincent, Rich, and Kathy discuss Cotia virus, a new poxvirus, Orf virus infections associated with handling goats and lamb, and the innate immune response to prions. Links for this episode: Cotia virus (J Virol) Human Orf virus … Continue reading

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TWiV 180: Throwing IFIT at flu and holding a miR to HCV

Hosts: Vincent Racaniello, Alan Dove, and Rich Condit Vincent, Alan, and Rich review association of an interferon-induced protein with severe influenza, and stabilization of HCV RNA by a microRNA. Links for this episode: IFITM3 and severe influenza (Nature) Genetics of flu susceptibiligy (EurekAlert!) Stabilization of HCV RNA … Continue reading

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Trade Wind Tree, South Point, Hawaii

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TWiV 179: Was ist ein virus?

Hosts: Vincent Racaniello, Alan Dove, Rich Condit, and Gertrud Radu Gertrud joins the TWiVoners to review how dengue virus infection of mosquitoes alters blood feeding behavior, and gene therapy as practiced by parasitoid wasps. Links for this episode: Renato Dulbecco, 1914-2012 (virology … Continue reading

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Colony Collapse Disorder: Dead Bees and Sloppy Science

A flurry of recent scientific papers, and a blizzard of subsequent news hype, has led a lot of people to conclude that the mystery of colony collapse disorder (CCD), which causes beehives to die suddenly, has been solved. Indeed, a … Continue reading

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